Symptoms
Prostate cancer
- Weak urine flow.
- Increased frequency of urination.
- Frequent urination at night (nocturia).
- Urinary urgency.
- Difficulty starting urination.
- Persistent pain in the lower back, pelvis, or thighs.

Testicular cancer
- Painless lump or swelling in the testicle.
- Feeling of heaviness in the scrotum, sudden fluid build-up.
- Aching in the lower abdomen or groin.
- Testicular cancer may produce hormones that cause breast enlargement or pain.
Penile cancer
- Thickening of the penile skin or appearance of rashes.
- Presence of lumps or ulcers on the penis, which may be painless or cause slight pain.
- Unpleasant odour.
- Unexplained discharge or bleeding from the penis or foreskin.
- Swelling of the lymph nodes in the groin.
Diagnosis
Prostate cancer
Initial screening
- Prostate-Specific Antigen test (PSA test).
Further tests / staging
- Biopsy.
- Chest X-ray.
- Isotope bone scan.
- PSMA Positron Emission Tomography-Computed Tomography (PSMA PET-CT).
- Computerised Tomography (CT scan).
- Magnetic Resonance Imaging (MRI) scan.
Testicular cancer
Initial screening
- Self-examination.
- Doctor’s examination.
- Scrotal ultrasound.
- Cancer index (i.e. tumour markers) AFP, β-hCG, and LDH are used to measure testicular cancer markers. However, tumour markers are generally used to track treatment response and recurrence rather than to diagnose cancer.
Further tests / staging
- Orchiectomy for testing.
- Chest X-ray.
- Computerised Tomography (CT scan).
- Magnetic Resonance Imaging (MRI) scan.
Penile cancer
Initial screening
- Self-examination.
- Doctor’s examination.
- Ultrasound.
Further tests / staging
- Biopsy.
- Computerised Tomography (CT scan).
- Magnetic Resonance Imaging (MRI) scan.
